Abstract
Introduction: laryngeal amyloidosis is an uncommon localized form of amyloidosis. The clinical symptomatology is not specific, and the diagnosis should be evoked in a persistent dysphonia.
Case report: A 45-year-old patient who had consulted for dysphonia lasting for 2 years. The nasofibroscopy showed an infiltrative lesion of the vocal cords. The laryngeal biopsy was performed and revealed laryngeal amyloidosis. Search for other locations was negative.
Conclusion: dysphonia is the most common symptom of laryngeal amyloidosis. Monitoring is extended because of the risk of recurrence and systemic dissemination.
References
Vignes S, Brasnu D, Hénégar C, Tiev KP, Généreau T, Cabane J. Amylose laryngée: Une cause rare de dysphonie. Rev Med Interne. 2000 Dec; 21(12):1121–5. https://doi.org/10.1016/s0248-8663(00)00272-1
Kharrat S, Besbes G, Trabelsi S, Lachkham A, Mekni A, Zainine R, et al. L’amylose Laryngée À Propos D’un Cas. J Tunisien d’ORL Chir Cervico-Faciale. 2006 Aug 26; 16(1):30–1. http://dx.doi.org/10.4314/jtdorl.v16i1.42058
Thompson LDR, Derringer GA, Wenig BM. Amyloidosis of the larynx: A clinicopathologic study of 11 cases. Mod Pathol. 2000 May;13(5):528–35. https://doi.org/10.1038/modpathol.3880092
Ayadhi oueslati Z, Ben azzouna H, Toumi S. Amylose laryngée à propos d'un cas. J Tun ORL. 2001; 07:36-9.
Talbot AR. Laryngeal amyloidosis. J Laryngol Otol. 1990 Feb; 104(2):147–9. https://doi.org/10.1017/s0022215100112113
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