Keywords
Laparoscopy
urine output
time
Categories
How to Cite
Abstract
Background: Laparoscopic cholecystectomy is one of the most common elective surgical procedures and is a minimally invasive option for patients with gallbladder diseases. Objectives: This study aimed to evaluate the effect of laparoscopic cholecystectomy and the duration of surgery on urine output among patients undergoing the procedure at Ali Ibn Abi Taleb Hospital in Zahedan (southeast Iran). Methods: Using a quasi-experimental design, 21 patients scheduled for laparoscopic cholecystectomy for various reasons at Ali Ibn Abi Taleb Hospital in Zahedan (Iran) were selected. To study renal function, blood samples were collected at three time points: before the surgery (time point 1), 30 minutes after insufflation of carbon dioxide into the abdomen (time point 2), and 30 minutes after removal of the last port (time point 3). Data were analyzed using repeated measures. Surgery time was measured in four steps: induction of anesthesia (step 1), insufflation of carbon dioxide (step 2), completion of surgery and gas removal (step 3), and extubation (step 4). Urine output was recorded at four time points. Results: According to the findings, laparoscopic cholecystectomy had no significant effect on urine output in our patients. Conclusions: Overall, despite observing some variations in BUN levels during laparoscopic surgery, creatinine levels remained stable. Therefore, laparoscopic cholecystectomy can be considered a safe surgical intervention with respect to renal function. The timing and duration of surgery did not affect renal function tests or urine output.
References
- Mendez-Sanchez N, Chavez-Tapia NC, Motola-Kuba D, Sanchez-Lara K, Ponciano-Rodriguez G, Baptista H, et al. Metabolic syndrome as a risk factor for gallstone disease.World J Gastroenterol. 2005;11(11):1653– 7. doi: 10.3748/wjg.v11.i11.1653. [PubMed: 15786544]. [PubMed Central: PMC4305948].
- Petelin JB. Surgical management of common bile duct
stones. Gastrointest Endoscopy. 2002;56(6B):S183–9. doi:
1067/mge.2002.1290131.
-Lammert F, Sauerbruch T. Mechanisms of disease: the genetic epidemiology of gallbladder stones. Nat Clin Pract Gastroenterol Hepatol. 2005;2(9):423–33. doi: 10.1038/ncpgasthep0257. [PubMed: 16265433].
-Volzke H, Baumeister SE, Alte D, Hoffmann W, Schwahn C, Simon P,et al. Independent risk factors for gallstone formation in a region with high cholelithiasis prevalence. Digestion. 2005;71(2):97–105. doi:10.1159/000084525. [PubMed: 15775677].
- Agrawal S, Jonnalagadda S. Gallstones, from gallbladder to gut. Postgraduate Med. 2015;108(3):143–53. doi: 10.3810/pgm.2000.09.1.1212.
- Das NT, Deshpande C. Effects of Intraperitoneal Local Anaesthetics Bupivacaine and Ropivacaine versus Placebo on Postoperative Pain after Laparoscopic Cholecystectomy: A Randomised Double Blind Study. J Clin Diagn Res. 2017;11(7):UC08–12. doi:10.7860/JCDR/2017/26162.10188. [PubMed: 28893013]. [PubMed Central: PMC5583910].
- Shiva A. The predictive factors for the success of laparoscopic cholecystectomy in patients with acute cholecystitis referring to the Qazvin province. Ghazvin Univ Med Sci. 2018.
-Bessler M, Stevens PD, Milone L, Hogle NJ, Durak E, Fowler D. Multimedia.article: Transvaginal laparoscopic cholecystectomy: laparoscopically assisted. Surg Endosc. 2008;22(7):1715–6. doi: 10.1007/s00464-008- 9779-1. [PubMed: 18322746].
-Joris JL. Anesthesia for Laparoscopic Surgery. Miller’s Anesthesia.7th ed. Churchill livingstone: Elseviere; 2010. p. 2185–202. doi:10.1016/b978-0-443-06959-8.00068-6.
- Townsend CMBR, Evers BM, Mattox K. Sabiston Textbook of surgery. Canada: Elsevier; 2010. p. 2185–6.
- ChangWT,Lee KT,HuangMC,ChenJS, Chiang HC,KuoKK, et al.The impact of body mass index on laparoscopic cholecystectomy in Taiwan:an oriental experience. J Hepatobiliary Pancreat Surg. 2009;16(5):648–54. doi: 10.1007/s00534-009-0102-x. [PubMed: 19387531].
- Picchio M, De Angelis F, Zazza S, Di Filippo A, Mancini R, Pattaro G, et al. Drain after elective laparoscopic cholecystectomy. A random- ized multicentre controlled trial. Surg Endosc. 2012;26(10):2817–22. doi: 10.1007/s00464-012-2252-1. [PubMed: 22538671].
- Karaca O, Pinar HU, Turk E, Dogan R, Ahiskalioglu A, Solak SK. Effects of Single-Dose Preemptive Pregabalin and Intravenous Ibuprofen on Postoperative Opioid Consumption and Acute Pain after Laparoscopic Cholecystectomy. J Invest Surg. 2019;32(3):189–95. doi: 10.1080/08941939.2017.1386738. [PubMed: 29157034].
- Lai H, Mo X, Yang Y, Xiao J, He K, Chen J, et al. Association between duration of carbon dioxide pneumoperitoneum during laparoscopic abdominal surgery and hepatic injury: a meta-analysis. PLoS One. 2014;9(8). e104067. doi: 10.1371/journal.pone.0104067. [PubMed: 25110982]. [PubMed Central: PMC4128655].
- Ntourakis D, Sergentanis TN, Georgiopoulos I, Papadopoulou E, Liasis L, Kritikos E, et al. Subclinical activation of coagulation and fibrinolysis in laparoscopic cholecystectomy: do risk factors exist? Int J Surg. 2011;9(5):374–7. doi: 10.1016/j.ijsu.2011.02.011. [PubMed: 21371576].
- Demiryas S, Donmez T, Erdem VM, Erdem DA, Hatipoglu E, Ferahman S, et al. Comparison of the effects of spinal epidural and general anesthesia on coagulation and fibrinolysis in laparoscopic cholecystectomy: a randomized controlled trial: VSJ Competition, 2(nd) place. Wideochir Inne Tech Maloinwazyjne. 2017;12(3):330–40.
doi: 10.5114/wiitm.2017.70249. [PubMed: 29062459].[PubMedCentral:
PMC5649509].
-Ignacio Aguirre–Allende1,*, Lander Gallego–Otaegui2,Jose Luis Elosegui–Aguirrezabala1, Carlos Placer–Galán1, and Jose Maria Enriquez–Navascués1. Laparoscopy-induced severe renal failure after appendectomy. Journal of Surgical Case Reports, 2019;3, 1–3. doi: 10.1093/jscr/rjz079.Case Report.
-Sophie de Seigneux1 , Claude-Eric Klopfenstein2 , Christophe Iselin3 and Pierre-Yves Martin1. The risk of acute kidney injury following laparoscopic surgery in a chronic kidney disease patient. NDT Plus (2011) 4: 339–341 doi: 10.1093/ndtplus/sfr071 Advance Access publication 17 July 2011 Teaching Point (Section Editor: A. Meyrier).
- Papaziogas B, Koutelidakis I, Kabaroudis A, Galanis I, Paraskevas G, Vretzakis G, et al. Modifications of coagulation and fibrinolysis mechanism in laparoscopic vs. open cholecystectomy. Hepatogastroenterology. 2007;54(77):1335–8. [PubMed: 17708249].
- Rodrigo Moreira e Lima,I* Lais Helena Camacho Navarro,I Giane Nakamura,II Daneshvari R. Solanki,III Yara Marcondes Machado Castiglia,I Pedro Tadeu Galva˜o Vianna,I Eliana Marisa GanemI. Serum cystatin C is a sensitive early marker for changes in the glomerular filtration rate in patients undergoing laparoscopic surgery.
- Examining the Effect of Laparoscopic Cholecystectomy on Coagulation Tests among Patients Undergoing the Surgery in Ali Ibn Abi Taleb Hospital in Zahedan in 2018. Ahmad Reza Shahraki 1, *, Ali Reza Khazayi 1, Mahdi Mohammadi 2, Elham Shahraki 3, Elahe Shahraki 4 and Abbas Ali Niaz. Zahedan J Res Med Sci. 2021 July; 23(3):e92588.
- Laparoscopic Cholecystectomy Effects on Renal Function Tests Among Patients Undergoing the Surgery in Ali Ibn Abi Taleb Hospital in Zahedan (South East of Iran) In 2018. Ahmad Reza Shahraki1*, Elham Shahraki2, Mahdi Mohammadi3, Reza Abaee4, Elahe Shahraki5, Ali Reza Khazayi1, Abbas Ali Niazi6. Clinical Medicine and Health Research Journal (CMHRJ) Volume 03, Issue 06, November - December, 2023 Page No. 632-636.
-Toleska M, Dimitrovski A. Is Opioid-Free General Anesthesia More Superior for Postoperative Pain Versus Opioid General Anesthesia in Laparoscopic Cholecystectomy? Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2019 Oct 1;40(2):81-87. doi: 10.2478/prilozi-2019-0018. PMID: 31605587.
-Gifford E, Kim DY, Nguyen A, Kaji AH, Nguyen V, Plurad DS, de Virgilio C. The effect of residents as teaching assistants on operative time in laparoscopic cholecystectomy. Am J Surg. 2016 Jan;211(1):288-93. doi: 10.1016/j.amjsurg.2015.06.019. Epub 2015 Aug 12. PMID: 26343854.
-Bourakkadi Idrissi M, El Bouhaddouti H, Mouaqit O, Ousadden A, Benjelloun EB. Impact of Resident Post-Graduate Year on Laparoscopic Cholecystectomy Outcomes. Cureus. 2023 Mar 24;15(3):e36644. doi: 10.7759/cureus.36644. PMID: 37155448; PMCID: PMC10122960.
-Sousa JHB, Tustumi F, Steinman M, Santos OFPD. Laparoscopic cholecystectomy performed by general surgery residents. Is it safe? How much does it cost? Rev Col Bras Cir. 2021 May 17;48:e20202907. doi: 10.1590/0100-6991e-20202907. PMID: 34008798; PMCID: PMC10683462.
-Cano ME, Uad P, Ardiles V, Sanchez Claria R, Mazza O, Palavecino M, de Santibañes E, Pekolj J, de Santibañes M. Impact of resident involvement on patient outcomes in laparoscopic cholecystectomy of different degrees of complexity: analysis of 2331 cases. Surg Endosc. 2022 Dec;36(12):8975-8980. doi: 10.1007/s00464-022-09349-w. Epub 2022 Jun 10. PMID: 35687252.
-Iossa A, Micalizzi A, Giuffrè M, Ciccioriccio MC, Termine P, De Angelis F, Boru CE, Di Buono G, Salzano A, Chiozza M, Agostini C, Silvestri V, Agrusa A, Anania G, Bracale U, Coratti F, Cavallaro G, Corcione F, Morino M, Silecchia G. Multicenter retrospective cohort Italian study on elective laparoscopic cholecystectomy performed by the surgical residents. Langenbecks Arch Surg. 2022 Dec 29;408(1):3. doi: 10.1007/s00423-022-02738-8. Erratum in: Langenbecks Arch Surg. 2023 Feb 16;408(1):92. doi: 10.1007/s00423-023-02824-5. PMID: 36577814.
-Singer KE, Baker JE, Elson NC, Wallen TE, Salvator A, Quillin RC, Sussman JJ, Makley AT, Goodman MD. How Informed Is Your Informed Consent: Evaluating Differences Between Resident and Attending Obtained Consents for Cholecystectomy. J Surg Educ. 2022 Nov-Dec;79(6):1509-1515. doi: 10.1016/j.jsurg.2022.07.021. Epub 2022 Aug 24. PMID: 36030182.
-White EM, Esposito AC, Kurbatov V, Wang X, Caty MG, Laurans M, Yoo PS. How I Learned is How I Teach - Perspectives on How Faculty Surgeons Approach Informed Consent Education. J Surg Educ. 2022 Nov-Dec;79(6):e181-e193. doi: 10.1016/j.jsurg.2022.09.001. Epub 2022 Oct 15. PMID: 36253332.
-Miura da Costa K, Saxena AK. Complications in pediatric laparoscopic cholecystectomy: systematic review. Updates Surg. 2021 Feb;73(1):69-74. doi: 10.1007/s13304-020-00888-2. Epub 2020 Sep 17. PMID: 32939742.
-Almeida RQ, Gerardi Filho VA, Dias JLF, Peres MCT, Waisberg J. Laparoscopic cholecystectomy for symptomatic cholelithiasis in children and adolescents: analysis of 50 cases from a single institution. Acta Cir Bras. 2024 Jul 22;39:e394124. doi: 10.1590/acb394124. PMID: 39046043; PMCID: PMC11262753.
-Eva I, Rosario V, Cesare S, Clarissa V, Federica LP, Rosaria CR, Emma C, Veronica V. Hemocoagulative Modifications after Laparoscopic Surgery at Different Pneumoperitoneum Pressure Settings. Int J Surg Protoc. 2022 Jun 14;26(1):41-48. doi: 10.29337/ijsp.173. PMID: 35800883; PMCID: PMC9205367.
- Kulaçoğlu H, Dener C, Kama NA. Urinary retention after elective cholecystectomy. Am J Surg. 2001 Sep;182(3):226-9. doi: 10.1016/s0002-9610(01)00703-6. PMID: 11587682.
- Hata T, Noda T, Shimizu J, Hatano H, Dono K. Omitting perioperative urinary catheterization in laparoscopic cholecystectomy: a single-institution experience. Surg Today. 2017 Aug;47(8):928-933. doi: 10.1007/s00595-016-1454-x. Epub 2016 Dec 9. PMID: 27943036.
- Zhang YF, Li XY, Liu XY, Zhang Y, Gong LR, Shi J, Du SH, He SM, Li C, Li YT, Li N, Liu SS, Wu Y, Xie ZL, Pei ZC, Yu JB. Transcutaneous Electrical Acupoints Stimulation Improves Spontaneous Voiding Recovery After Laparoscopic Cholecystectomy: A Randomized Clinical Trial. World J Surg. 2023 May;47(5):1153-1162. doi: 10.1007/s00268-023-06924-7. Epub 2023 Feb 6. PMID: 36745198.
- Zhang Y, Gong L, Zhang Y, Dong S, Shi J, Li X, Guo Y, He S, Wu X, Liu S, Liu H, Zhang L, Yu J. Effect of Transcutaneous Acupoint Electrical Stimulation on Urinary Retention and Urinary ATP in Elderly Patients After Laparoscopic Cholecystectomy: A Prospective, Randomized, Controlled Clinical Trial. Clin Interv Aging. 2022 Dec 1;17:1751-1760. doi: 10.2147/CIA.S382912. PMID: 36479561; PMCID: PMC9722321.
- Cai YC, Lin YL, Yin SJ, Ding Y, Wu W, Mo KL, Shi JD, Song HJ. Effect of transcutaneous electrical acupoint stimulation based on the theory of "qi ascending and descending movement" on autonomic nervous system and gastrointestinal function in patients after general anesthesia laparoscopic cholecystectomy. Zhen Ci Yan Jiu. 2024 Mar 25;49(3):283-288. English, Chinese. doi: 10.13702/j.1000-0607.20221402. PMID: 38500325.
- Mi Z, Gao J, Chen X, Ge Y, Lu K. [Effects of transcutaneous electrical acupoint stimulation on quality of recovery during early period after laparoscopic cholecystectomy]. Zhongguo Zhen Jiu. 2018 Mar 12;38(3):256-60. Chinese. doi: 10.13703/j.0255-2930.2018.03.007. PMID: 29701042.
- Chang DT, Kirsch AJ, Sawczuk IS. Oliguria during laparoscopic surgery. J Endourol. 1994 Oct;8(5):349-52. doi: 10.1089/end.1994.8.349. PMID: 7858621.
-de Barros RF, Miranda ML, de Mattos AC, Gontijo JA, Silva VR, Iorio B, Bustorff-Silva JM. Kidney safety during surgical pneumoperitoneum: an experimental study in rats. Surg Endosc. 2012 Nov;26(11):3195-200. doi: 10.1007/s00464-012-2322-4. Epub 2012 May 19. PMID: 22609982.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2025 Ahmad Reza Shahraki
