Pulmonary Tuberculosis and Diabetes Mellitus Profile
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Keywords

Tuberculosis
Diabetes
Risk factor
Prevalence

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How to Cite

1.
Kouismi H, Hammi S, Bouti K, Rhanim A, Ataouna K, Razine R, Bourkadi JE. Pulmonary Tuberculosis and Diabetes Mellitus Profile. Integr J Med Sci [Internet]. 2015 Jun. 30 [cited 2024 Nov. 21];2:11-5. Available from: https://mbmjpress.com/index.php/ijms/article/view/19

Abstract

Background: About 95% of patients with tuberculosis (TB) and 70% of patients with diabetes mellitus (DM) live in low and middle-income countries. As a result, DM and TB are increasingly occurring together. The risk of tuberculosis is two to five times greater in patients with diabetes. The purpose of this study is to analyze the characteristics of pulmonary tuberculosis in patients with diabetes and to evaluate the impact of tuberculosis on diabetes control.
Patients and Methods: This is a retrospective study of 80 patients with confirmed pulmonary tuberculosis, comparing 30 patients with diabetes with 50 without diabetes.
Results: Diabetes was more frequent in older patients with tuberculosis and in male patients. 63,3% had type 2 diabetes. Tuberculosis symptoms did not differ between the two groups. Involvement of basal segments of the lower lobes and cavitation occurred more frequently in patients with diabetes, but this difference was not significant. The time for conversion to negative of sputum culture was longer in control patients (44,1 ± 20,2 days) than in case (36 ± 18.3) (p = 0.08).
Conclusion: Tuberculosis is frequently associated with diabetes mainly in low-income countries. The problem with this association could be accentuated in the future.

https://doi.org/10.15342/ijms.v2i1.68
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References

Banerjee S, Banerjee M. Diabetes and tuberculosis interface. J Indian Med Assoc. 2005 Jun; 103(6):318-320, 322 passim.

Jeon CY, Murray MB. Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies. PLoS Med. 2008 Jul 15; 5(7):e152. https://doi.org/10.1371/journal.pmed.0050152

Raghuraman S, Vasudevan P, Govindarajan S, Chinnakali P, Panigrahi K C. Prevalence of Diabetes Mellitus among Tuberculosis Patients in Urban Puducherry. N Am J Med Sci. 2014 Jan; 6(1): 30–4. https://doi.org/10.4103/1947-2714.125863

Touré NO, Dia Kane Y, Diatta A, Ba Diop S, Niang A, Ndiaye EM et al. Tuberculose et diabète. Rev Mal Repir. 2007 Sep; 24(7):869-75. https://doi.org/10.1016/s0761-8425(07)91389-3

Wang CS, Chen HC, Yang CJ, Tsai JR, Chong LW, Hwang JJ et al. Clinical characteristics of pulmonary tuberculosis patients from a southern Taiwan hospitalbased survey. Kaohsiung J Med Sci. 2008 Jan; 24(1): 17–24. https://doi.org/10.1016/s1607-551x(08)70068-8

Stevenson CR, Forouhi NG, Roglic G, Williams BC, Lauer JA, Dye C et al. Diabete and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. BMC Public Health. 2007 Sep 6; 7(1):234. https://doi.org/10.1186/1471-2458-7-234

Stevenson CR, Forouhi NG, Roglic G, Williams BC, Lauer JA, Dye C, et al. Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. BMC Public Health 2007 Sep 6; 7(1):234. https://doi.org/10.1186/1471-2458-7-234

Mugusi F, Swai AB, Alberti KG, McLarty DG. Increased prevalence of diabetes mellitus in patients with pulmonary tuberculosis in Tanzania. Tubercle. 1990 Dec; 71(4):271–6. https://doi.org/10.1016/0041-3879(90)90040-f

Pérez-Guzmàn C, Torres-Cruz A, Villarreal- Velarde H, Salazar-Lezama MA, Vargas MH. Atypical radiological images of pulmonary tuberculosis in 192 diabetic patients: a comparative study. Int J Tuberc Lung Dis. 2001 May; 5(5):455-61. [Accessed 28th May 2021]. Available from: https://www.ingentaconnect.com/content/iuatld/ijtld/2001/00000005/00000005/art00010

Mboussa J, Monabeka H, Kombo M, Yokolo D, YokaMbio D, Yala F. Évolution de la tuberculose pulmonaire chez les diabétiques. Rev Pneumol Clin. 2003 Feb; 59(1):39-44.

Maâlej S, Belhaoui N, Bourguiba M, Mahouachi R, Chtourou A, Taktak S, et al. [Pulmonary tuberculosis and diabetes. A retrospective study of 60 patients in Tunisia]. Presse Med. 2009 Jan; 38(1): 20–4. https://doi.org/10.1016/j.lpm.2008.05.011

Guptan A, Shah A. Tuberculosis and Diabetes: An Appraisal. Ind J Tub. 2000; 47(3):2–8.:

Ponce-De-Leon A, Garcia-Garcia Md Mde L, GarciaSancho MC, Gomez-Perez FJ, Valdespino-Gomez JL, Olaiz-Fernandez G, et al. Tuberculosis and diabetes in southern Mexico. Diabetes Care. 2004 Jul; 27(7):1584–90. https://doi.org/10.2337/diacare.27.7.1584

Alisjahbana B, Sahiratmadja E, Nelwan EJ, Purwa AM, Ahmad Y, Ottenhoff TH, et al. The effect of type 2 diabetes mellitus on the presentation and treatment response of pulmonary tuberculosis. Clin Infect Dis. 2007 Aug 15; 45(4):428–35. https://doi.org/10.1086/519841

Baldé NM, Camara A, Camara LM, Diallo MM, Kaké A, Bah-Sow O Y. Associated tuberculosis and diabetes in Conakry, Guinea: prevalence and clinical characteristics. Int J Tuberc Lung Dis.2006 Sep; 10(9): 1036-40. [Accessed 28th May 2021]. Available From: https://www.ingentaconnect.com/contentone/iuatld/ijtld/2006/00000010/00000009/art00017

Feleke Y, Abdulkadir J, Aderaye G. Prevalence and clinical features of tuberculosis in Ethiopian diabetic patients. East Afr Med J. 1999 Jul; 76(7): 361-4.

Ezung T, Devi TN, Singh TN, Singh TB. Pulmonary tuberculosis and diabetes mellitus—a study. J Indian Med Assoc. 2002 Jun; 100(6): 378-9.

Dooley EK, Chaisson ER. Tuberculosis and diabetes mellitus: convergence of two epidemics. The Lancet Infectious Dis. 2009 Dec; 9(12): 737–46. https://doi.org/10.1016/s1473-3099(09)70282-8

Wang CS, Yang CJ, Chen HC, Chuang SH, Chong IW, Hwang JJ, Et at. Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis. Epidemiol Infect. 2009 Feb; 137(2):203–10. https://doi.org/10.1017/s0950268808000782

Nissapatorn V, Kuppusamy I, Jamaiah I, Fong MY, Rohela M, Anuar AK. Tuberculosis in diabetic patients: a clinical perspective. Southeast Asian J Trop Med Public Health. 2005; 36 Suppl 4:213–20.

[Accessed 28th May 2021]. Available from: https://www.tm.mahidol.ac.th/seameo/2005_36_spp4/36sup4_213.pdf

Sosman M, Steidl J. Diabetic tuberculosis. Am J Roentgenol 1927; 17- 625.

Weaver RA. Unusual radiographic presentation of pulmonary tuberculosis in diabetic patients. Am Rev Respir Dis.1974 Jan; 109(1):162–3. https://doi.org/10.1164/arrd.1974.109.1.162

Marais RM. Diabetes mellitus in black and coloured tuberculosis patients. S Afr Med J. 1980 Mar 29; 57(13):483– 84. [Accessed 28th May 2021]. Available from: https://journals.co.za/doi/pdf/10.10520/AJA20785135_16011

Perez-Guzman C, Torres-Cruz A, Villarreal- Velarde H, Vargas MH. Progressive agerelated changes in pulmonary tuberculosis images and the effect of diabetes. Am J Respir Crit Care Med. 2000 Nov; 162(5):1738-40. https://doi.org/10.1164/ajrccm.162.5.2001040

Bacakoglu F, Kaçmaz Basoglu O, Cok G, Saymer A, Ates M. Pulmonary tuberculosis in patients with diabetes mellitus. Respiration. 2001; 68(6):595-600. https://doi.org/10.1159/000050578

Nissapatorn V, Kuppusamy I, Jamaiah I, Fong MY, Rohela M, Anuar K. Tuberculosis in diabetic patients: A clinical perspective. Southeast Asian J Trop Med Public Health. 2005; 36 Suppl 4:213-20. [Accessed 28th May 2021]. Available from: http://eprints.um.edu.my/3266/

Mboussa J, Monabeka H, Kombo M, Yokolo D, YokaMbio A, Yala F. Course of pulmonary tuberculosis in diabetics. Rev Pneumol Clin 2003 Feb; 59(1):39–44.

Wang CS, Yang CJ, Chen HC, Chuang SH, Chong IW, Hwang JJ, et al. Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis. Epidemiol Infect. 2009 Feb; 137(2):203–10. https://doi.org/10.1017/s0950268808000782

Hendy M, Stableforth D. The effect of established diabetes mellitus on the presentation of infiltrative pulmonary tuberculosis in the immigrant Asian community of an inner city area of the United Kingdom. Br J Dis. Chest. 1983 Jan; 77(1):87–90. https://doi.org/10.1016/0007-0971(83)90010-4

Singla R, Khan N, Al-Sharif N, Ai-Sayegh MO, Shaikh MA, Osman MM. Influence of diabetes on manifestations and treatment outcome of pulmonary TB patients. Int J Tuberc Lung Dis.2006 Jan: 10(1):74-9. [Accessed 28th May 2021]. Available from: https://www.ingentaconnect.com/content/iuatld/ijtld/2006/00000010/00000001/art00014

Banu Rekha VV, Balasubramaniam R, Swaminathan S, Ramachandran R, Rahman F, Sundaram V Sputum conversion at the end of intensive phase of category-1 regim in treatment of pulmonary tuberculosis patients with diabetes mellitus or HIVinfection: An analysis of risk factors. Indian J Med Res. 2007; 126 (5): 452-8. [Accessed 28th May 2021]. Available from: http://eprints.nirt.res.in/795/

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Copyright (c) 2015 Hatim Kouismi et al.

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