Keywords
Surgery
Pulmonary localization
Scapular localization
Categories
How to Cite
Abstract
Background: Desmoid tumors are rare and represent 0.03% of all solid tumors. Their histology is benign but they are willingly aggressive with significant locoregional invasions and frequent recurrences.
Case presentation: We report the case of a 52-year-old patient who presented with a scapular and pulmonary localization of this tumor, but was stable over time. In view of potentially delaying surgery and stability of the lesions, simple monitoring was decided. The lesions are currently stable, two years after diagnosis. We discuss the clinical, radiological, and therapeutic characteristics of this type of tumor, in the light of data from the literature.
Conclusion: Desmoid tumors are rare, benign but aggressive. Surgery is the main treatment but is often decaying. Simple monitoring can be scheduled in case of less aggressive tumors.
References
Shields CJ, Winter DC, Kirwan WO, Redmond HP. Desmoid tumours. Eur J Surg Oncol. 2001 Dec; 27(8):701–6. https://doi.org/10.1053/ejso.2001.1169
De Camargo VP, Keohan ML, D’Adamo DR, Antonescu CR, Brennan MF, Singer S, et al. Clinical outcomes of systemic therapy for patients with deep fibromatosis (desmoid tumor). Cancer. 2010 May; 116(9):2258–65. https://doi.org/10.1002/cncr.25089
Mignot L. Orphanet: Tumeur desmoïde [Internet]. [Accessed 2021 Sep 02]. Available from: https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=873
Kasper B, Baumgarten C, Garcia J, Bonvalot S, Haas R, Haller F, et al. An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma Patients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG). Ann Oncol. 2017 Oct 1;28(10):2399-2408. https://doi.org/10.1093/annonc/mdx323
Méndez-Fernández MA, Gard DA. The desmoid tumor: "benign" neoplasm, not a benign disease. Plast Reconstr Surg. 1991 May; 87(5):956–60. https://doi.org/10.1097/00006534-199105000-00025
Ganeshan D, Amini B, Nikolaidis P, Assing M, Vikram R. Current Update on Desmoid Fibromatosis. J Comput Assist Tomogr. 2019 Jan-Feb; 43(1): 29–38. https://doi.org/10.1097/rct.0000000000000790
Sakorafas GH, Nissotakis C, Peros G. Abdominal desmoid tumors. Surg Oncol; 2007 Aug; 16(2):131-42. https://doi.org/10.1016/j.suronc.2007.07.009
Nieuwenhuis MH, Casparie M, Mathus-Vliegen LMH, Dekkers OM, Hogendoorn PCW, Vasen HFA. A nation-wide study comparing sporadic and familial adenomatous polyposis-related desmoid-type fibromatoses. Int J Cancer. 2011 Jul 1; 129(1):256–61. https://doi.org/10.1002/ijc.25664
Wilcken N, Tattersall MH. Endocrine therapy for desmoid tumors. Cancer. 1991 Sep 15;68(6):1384-8. https://doi.org/10.1002/1097-0142(19910915)68:6%3C1384::aid-cncr2820680634%3E3.0.co;2-f
Stoeckle E, Coindre JM, Longy M, Bui Nguyen Binh M, Kantor G, Kind M, et al. A critical analysis of treatment strategies in desmoid tumours: a review of a series of 106 cases. Eur J Surg Oncol. 2009 Feb; 35(2):129–34. https://doi.org/10.1016/j.ejso.2008.06.1495
Chew C, Reid R, O’Dwyer PJ. Evaluation of the long term outcome of patients with extremity desmoids. Eur J Surg Oncol. 2004 May; 30(4):428–32. https://doi.org/10.1016/j.ejso.2004.01.010
Kaplan J, Davidson T. Intrathoracic desmoids: Report of two cases. Thorax. 1986 Nov; 41(11):894–5.https://doi.org/10.1136/thx.41.11.894
Easter DW, Halasz NA. Recent trends in the management of desmoid tumors. Summary of 19 cases and review of the literature. Ann Surg. 1989 Dec; 210(6):765–9. https://doi.org/10.1097/00000658-198912000-00012
Chevrel JP, Sarfati E, Saglier J, Kemeny JL. [Desmoid tumor and Gardner’s syndrome. Apropos of a case]. J Chir (Paris). 1983 Mar; 120(3):159-64.
Robinson WA, McMillan C, Kendall A, Pearlman N. Desmoid tumors in pregnant and postpartum women. Cancers (Basel). 2012 Feb 21; 4(1):184–92. https://doi.org/10.3390/cancers4010184
Thene M, Thevenot J, Monrozies X, Fournie A. [Desmoid tumors of the anterior abdominal wall. Apropos of a case]. Ann Chir. 1989;43(4) :295-8.
Montagliani L, Duverger V. Les tumeurs desmoïdes. J Chir. 2008 Feb; 145(1): 20-26. https://doi.org/10.1016/S0021-7697(08)70288-6
Muller E, Castagnaro M, Yandel DW, Wolfe HJ, Alman BA. Molecular genetic and immunohistochemical analysis of the tumor suppressor genes Rb and p53 in palmar and aggressive fibromatosis. Diagnostic Mol Pathol. 1996 Sep;5(3):194-200. https://doi.org/10.1097/00019606-199609000-00008
Kawamura M, Seki M, Yoshizu A, Naruke M, Yamahata J, Izumi Y, et al. [Reconstruction of chest wall defects with autogenous ribs grafts]. Kyobu Geka. 1996 Jan; 49(1):53–6.
Allen PJ, Shriver CD. Desmoid Tumors of the Chest Wall. Semin Thorac Cardiovasc Surg. 1999 Jul; 11(3):264–9. https://doi.org/10.1016/s1043-0679(99)70067-5
Chia Chi Kao, Rand RP, Stridde BC, Marchioro TL. Techniques in the composite reconstruction of extensive thoracoabdominal tumor resections. J Am Coll Surg. 1995 Feb;180(2):146–9.
Sherman NE, Romsdahl M, Evans H, Zagars G, Oswald MJ. Desmoid tumors: a 20-years radiotherapy experience. J Radiat Oncol Biol Phys. 1990 Jul; 19(1):37-40. https://doi.org/10.1016/0360-3016(90)90131-3
ESMO/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014 Sep; 25 Suppl 3:iii102-12. https://doi.org/10.1093/annonc/mdu254
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