The Photodynamic Treatment of Oral Lichen Planus: A Literature Review
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Keywords

Lichen planus
Photodynamic Treatment
Photosensitizers

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Azzouzi A, El Harti K. The Photodynamic Treatment of Oral Lichen Planus: A Literature Review. Integr J Med Sci [Internet]. 2021 Nov. 7 [cited 2024 Nov. 21];8. Available from: https://mbmjpress.com/index.php/ijms/article/view/485

Abstract

Lichen planus (LP) is a chronic, relapsing, non-infectious inflammatory disease affecting the skin and mucous membranes. The exact origin of oral lichen planus (OLP) is not well known. Complete spontaneous healing is rare. The treatment of oral OLP is palliative; there is no curative treatment so far which is a therapeutic challenge for practitioners. The goals of treatment are the control of pain, signs, and symptoms. Local corticosteroids remain the first-line treatment. In case of failure of drug therapy, other treatments can be considered such as photodynamic therapy (PDT). Material and methods: Our work was carried out using the PubMed, ScienceDirect, and EBSCO search engines to explore the literature on the efficacy of PDT in the treatment of lichen planus. Conclusion: PDT appears to have some effect in the treatment of OLP in adult patients. However, further randomized controlled trials with a long follow-up period, standardized PDT parameters, and comparison of PDT efficacy with steroid therapy are warranted to obtain strong conclusions in this regard.

https://doi.org/10.15342/ijms.2021.485
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References

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Copyright (c) 2021 Asma Azzouzi, Karima El Harti

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